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DC Field | Value | Language |
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dc.rights.license | http://creativecommons.org/licenses/by-nc-nd/4.0 | es_MX |
dc.creator | BETSABE RODRIGUEZ PEREZ | es_MX |
dc.date.accessioned | 2020-08-10T16:08:34Z | - |
dc.date.available | 2020-08-10T16:08:34Z | - |
dc.date.issued | 2020-04-29 | - |
dc.identifier.uri | http://repositorio.ugto.mx/handle/20.500.12059/2240 | - |
dc.description.abstract | La actividad antibacteriana de los propóleos se relaciona con el contenido de compuestos fenólicos y flavonoides; sin embargo, no todos los propóleos presentan esta propiedad debido a la ausencia o baja cantidad de estos compuestos, pero se puede incrementar con la adición de chalconas sintéticas. Se sintetizaron tres chalconas: 1,3-difenilpropil-2E-1-ona (PLCR-1); y dos análogos con sustituyentes hidroxilo: 1-(3,4-dihidroxifenil)-4-(2,4,6-trihidroxifenil)prop-2E-en-1-ona (PLCR-2) y 1-(3,4-dihidroxifenil)-4-(2,4-dihidroxifenil)prop-2E-en-1-ona (PLCR-3) que se adicionaron en distintas proporciones a dos propóleos, uno del estado de Guanajuato (sin flavonoides) y otro del Estado de México (con flavonoides) para evaluar la actividad antibacteriana contra cepas de referencia de Staphylococcus aureus y de Escherichia coli, utilizando el método Kirby Bauer. Los resultados muestran que únicamente la chalcona PLCR-3 potencializó el efecto antibacteriano de ambas muestras frente a S. aureus. El incremento de la actividad antibacteriana de un propóleo con la adición de chalconas sintéticas está en relación con el microorganismo evaluado y la proporción utilizada / Betsabé Rodríguez Pérez, José Guillermo Penieres Carrillo, María Margarita Canales Martínez, Tonatiuh Alejandro Cruz Sánchez. | es_MX |
dc.language.iso | spa | es_MX |
dc.publisher | Universidad de Guanajuato | es_MX |
dc.relation | https://doi.org/10.15174/au.2020.2849 | - |
dc.rights | info:eu-repo/semantics/openAccess | es_MX |
dc.source | Acta Universitaria: Multidisciplinary Scientific Journal. Vol. 30 (2020) | es_MX |
dc.title | Actividad antibacteriana de propóleos con la adición de chalconas sintéticas | es_MX |
dc.title.alternative | Antibacterial activity of propolis with the addition of synthetic chalcones | en |
dc.type | info:eu-repo/semantics/article | es_MX |
dc.creator.id | info:eu-repo/dai/mx/cvu/511917 | es_MX |
dc.subject.cti | info:eu-repo/classification/cti/2 | es_MX |
dc.subject.cti | info:eu-repo/classification/cti/32 | es_MX |
dc.subject.cti | info:eu-repo/classification/cti/2302 | es_MX |
dc.subject.cti | info:eu-repo/classification/cti/3209 | es_MX |
dc.subject.keywords | Propóleos | es_MX |
dc.subject.keywords | Chalconas | es_MX |
dc.subject.keywords | Actividad antibacteriana | es_MX |
dc.subject.keywords | Farmacognosia | es_MX |
dc.subject.keywords | Propolis | es_MX |
dc.subject.keywords | Chalcones | es_MX |
dc.subject.keywords | Antibacterial activity | es_MX |
dc.subject.keywords | Pharmacognosy | es_MX |
dc.type.version | info:eu-repo/semantics/publishedVersion | es_MX |
dc.creator.two | JOSE GUILLERMO PENIERES CARRILLO | es_MX |
dc.creator.three | MARIA MARGARITA CANALES MARTINEZ | es_MX |
dc.creator.idtwo | info:eu-repo/dai/mx/cvu/14194 | es_MX |
dc.creator.idthree | info:eu-repo/dai/mx/cvu/39686 | es_MX |
dc.description.abstractEnglish | The antibacterial activity of propolis is related to the content of phenolic compounds and flavonoids; however, not all propolis present this property because of the absence or low amount of these compounds, but it can be increased with the addition of synthetic chalcones. Three chalcones were synthesized: 1,3-diphenylpropyl-2E-1-one (PLCR-1); and two hydroxyl-replaced analogues: 1-(3,4-dihydroxyphenyl)-4-(2,4,6-trihydroxyphenyl)prop-2E-en-1- one (PLRC-2) and 1-(3,4-dihydroxyphenyl)-4-(2,4-dihydroxyphenyl)prop-2E-en- 1-one (PLRC-3)that were added in different proportions to two propolis, one from the State of Guanajuato (without flavonoids) and another from the State of Mexico (with flavonoids) aiming to evaluate antibacterial activity against reference strains of Staphylococcus aureus and Escherichia coli, using the Kirby Bauer method. The results show that only PLCR-3 chalcone strengthened the antibacterial effect of both samples against S. aureus. The increase of the antibacterial activity of a propolis with the addition of synth etic chalcones is relative to the evaluated microorganism and the proportion used / Betsabé Rodríguez Pérez, José Guillermo Penieres Carrillo, María Margarita Canales Martínez, Tonatiuh Alejandro Cruz Sánchez. | en |
Appears in Collections: | Revista Acta Universitaria |
Files in This Item:
File | Description | Size | Format | |
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Actividad antibacteriana de propóleos con la adición de chalconas sintéticas.pdf | 1.64 MB | Adobe PDF | View/Open |
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