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DC Field | Value | Language |
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dc.rights.license | http://creativecommons.org/licenses/by-nc-nd/4.0 | es_MX |
dc.contributor.author | José Genaro Carmona Gutiérrez | es_MX |
dc.contributor.author | Rafael Muñoz Bedolla | es_MX |
dc.contributor.author | Marco Antonio González Coronel | es_MX |
dc.creator | JOSE ALBINO MORENO RODRIGUEZ | es_MX |
dc.date.accessioned | 2022-05-23T05:41:03Z | - |
dc.date.available | 2022-05-23T05:41:03Z | - |
dc.date.issued | 2012-05 | - |
dc.identifier.uri | http://repositorio.ugto.mx/handle/20.500.12059/6255 | - |
dc.description.abstract | En los últimos 10 años los nanoreservorios a base de TiO2 han sido la punta para el desarrollo de nuevas y mejores alternativas hacia el control y posible “eliminación” de enfermedades que han azorado a la humanidad desde su existencia. En dicha búsqueda de contribuir con dichas expectativas, en esta primera etapa se sintetizaron nanoreservorios de TiO2 con NaHCO3 15% (NaHCO3-15/TiO2), con platino II al 0.1% (Pt-0.1/TiO2) y con NaHCO3 15% - platino II al 0.1% “in situ” (Pt-0.1-NaHCO3-15/TiO2) por sol-gel. La caracterizaron de los nanoreservorios fue por espectroscopia UV-VIS, FTIR y DRX. Se muestra que el TiO2 y el nanoreservorio de Pt-0.1/TiO2 son amorfos. Los nanoreservorios de NaHCO3-15/TiO2 y Pt-0.1-NaHCO3-15/TiO2 son cristalinos por la transformación de la sal ácida (NaHCO3) a TRONA (Na3 (CO3)(HCO3)•2H2O). La TRONA pudiera incrementar el tamaño promedio de partícula en los nanoreservorios Pt-0.1-NaHCO3-15/TiO2 a180 nm respecto a 130 nm (NaHCO3-15/TiO2) y a 50 nm (Pt-0.1/TiO2). | es_MX |
dc.language.iso | spa | es_MX |
dc.publisher | Universidad de Guanajuato | es_MX |
dc.relation | http://quimica.ugto.mx/index.php/nyt/article/view/215 | - |
dc.rights | info:eu-repo/semantics/openAccess | es_MX |
dc.source | Revista Enlace Químico, Vol. 4, Núm. 1, Mayo 2012 | es_MX |
dc.title | Síntesis y caracterización de nanoreservorios de TiO2 soportados con platino II y solución de bicarbonato de sodio | es_MX |
dc.title.alternative | Synthesis and characterization of TiO2nanoreservoirs supported by platinum II and sodium bicarbonate solution | en |
dc.type | info:eu-repo/semantics/article | es_MX |
dc.creator.id | info:eu-repo/dai/mx/cvu/121582 | es_MX |
dc.subject.cti | info:eu-repo/classification/cti/2 | es_MX |
dc.subject.keywords | Óxido de titanio (TiO2) | es_MX |
dc.subject.keywords | Bicarbonato de sodio (NaHCO3) | es_MX |
dc.subject.keywords | Platino (Pt) | es_MX |
dc.subject.keywords | Nanoreservorios | es_MX |
dc.subject.keywords | Proceso Sol-gel | es_MX |
dc.subject.keywords | Titanium dioxide (TiO2) | en |
dc.subject.keywords | Sodium bicarbonate (NaHCO3) | en |
dc.subject.keywords | Platinum (Pt) | en |
dc.subject.keywords | Nanoreservoirs | en |
dc.subject.keywords | Sol-gel process | en |
dc.type.version | info:eu-repo/semantics/publishedVersion | es_MX |
dc.creator.two | MARIA LUISA ROXANA LICONA IBARRA | es_MX |
dc.creator.three | JOSE GENARO CARMONA GUTIERREZ | es_MX |
dc.creator.four | EFRAIN RUBIO ROSAS | es_MX |
dc.creator.five | LILIAN AURORA MORENO RODRIGUEZ | es_MX |
dc.creator.idtwo | info:eu-repo/dai/mx/cvu/200792 | es_MX |
dc.creator.idthree | info:eu-repo/dai/mx/cvu/31797 | es_MX |
dc.creator.idfour | info:eu-repo/dai/mx/cvu/123665 | es_MX |
dc.creator.idfive | info:eu-repo/dai/mx/cvu/549541 | es_MX |
dc.description.abstractEnglish | In the past 10 years the nano-reservoirs based on TiO2 have taken the lead to develop new and better ways to control and possible "removal" of diseases that have bewildered mankind since its existence. In the seeking to contribute to those expectations, at this first stage we synthesized nanoreservoirs of TiO2 with NaHCO3 15% (NaHCO3-15/TiO2), with platinum II 0.1% (Pt-0.1/TiO2) and NaHCO3 15%-platinum II 0.1% “in situ” (Pt-0.1-NaHCO3-15/TiO2) by sol-gel. It is shown that TiO2 and Pt-0.1/TiO2 nanoreservoirs are amorphous and NaHCO3- 15/TiO2 and Pt-0.1-NaHCO3-15/TiO2 nanoreservoirs are crystalline. The NaHCO3-15/TiO2 and Pt-0.1-NaCO3-15/TiO2 nanoreservoirs are crystalline, because of the transformation of the acid salt (NaHCO3) to TRONA (Na3(CO3)(HCO3)•2H2O). The TRONA could increase the average particle size of the Pt-0.1-NaCO3-15/TiO2 nanoreservoirs to 180 nm in comparison to 130 nm (NaHCO3-15/TiO2) and 50 nm (Pt-0.1/TiO2). carrier, since it has a high hydrophilic behavior and it is used in the pharmaceutical industry as excipient or an active ingredient. In this work the PEG6000 mixed and later fused was fused with metronidazole for the obtention of solid dispersions. This drug is insoluble in water and it is employed as antiparasitic. In this work was preparated 1:0.25; 1:0.50; 1:0.75 solid dispersions of the drug. All the samples were characterized by DSC and XRD. It was observed that a part of the metronidazole is retained in the volume of PEG6000 and another part is fixed on it’s the surface. The evaluation of the dilution rate for the solutions (manufactured in tabs), shows a better profile of liberation, between 45% to 90 %, with respect to comparison with commercial presentations (from 29% to 56 %). This result was subject to simple regression analysis. | en |
Appears in Collections: | Revista Naturaleza y Tecnología |
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2_Síntesis y caracterización de nanoreservorios de TiO2.pdf | 748.25 kB | Adobe PDF | View/Open |
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